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The 12th International Conference on Next-generation computing, communication, Systems and Security (12th NSysS 2025) aims to provide a forum for researchers, practitioners, developers, and users from academia, industry, and government to interact, present, and exchange new research ideas and results. Its scope includes recent advances in both theoretical and experimental research addressing the rich space of networking system design, system security, AI for systems and networks, computing systems, and HCI system development across academia and industry. 12th NSysS 2025 will be held from December 18-20, 2025, in Sylhet, Bangladesh. It is the 12th event of this conference series.

• There will be a provision for online paper presentations if the authors won’t be able to be present in person due to unavoidable reasons.

Paper submission deadline:	September 01, 2025 (AoE)
Notification of paper acceptance:	November 01, 2025 (AoE)
Camera-ready content submission:	November 20, 2025 (AoE)
Poster submission deadline:	November 20, 2025 (AoE)
Notification of poster acceptance:	November 27, 2025 (AoE)
Program:	December 18-20, 2025

We solicit original technical papers articulating novel ideas, protocols, and algorithms with ground-breaking results and/or quantified experiences involving networking system design, system security, AI for systems and networks, computing systems, and HCI system development. The papers will be peer-reviewed and will be indexed by DBLP.